Common causes for Rosacea
Some studies show a fifty percent to ninety percent incidence of gastritis (diagnosed with gastroscopy or biopsy) in patients with rosacea and H.
Pylori is found very often, but others deny the association. One factor that has generated controversy is the possible pathogenic role played by Demodex folliculorum, a parasite of the normal flora of the sebaceous glands, this mite; however, after declining in number and effective treatments in patients with inflammatory phenomena Rosacea may exist in their absence.
It has been found with regard to psychogenic factors, although a small proportion of patients taking note of the stress factor as a cause of their illness.
There are many reasons that trigger rosacea flare as sun exposure, emotional stress, hot baths, alcohol, etc., based on this, scientists have conducted research on bacterial or parasitic infestations, abnormal blood vessels and lymphatic and immune and inflammatory relationship that occur at the endothelium and basement membrane of blood vessel primarily, his relationship with vasoactive substances or mediators as histamine, prostaglandins, serotonin, substance P, growth factor vascular endothelial FEV, Endoglin, Cathelicidins, Dermcidim, among the most important.
Histamine has vasoactive actions released by mast cells particularly active in the allergic reactions. Receptors are H1 and H2. The action of H1 is promoted by 2-methyl histamine that causes constriction of smooth muscle, increased vascular permeability and production of these prostaglandins may be increased in people with rosacea that is producing the facial flushing.
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